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Allyson S. C. Soon, Michael H. Smith, Emily S. Herman, L. Andrew Lyon and Thomas H. Barker Development of Self-Assembling Mixed Protein Micelles with Temperature-Modulated Avidities Advanced Healthcare Materials 2

Article first published online: 26 FEB 2013 | DOI: 10.1002/adhm.201200330

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Protein-based mixed micelles with variable avidities to fibrinogen at different temperature regimes are reported. Such a system has potential drug delivery applications as a blood circulating depot that will only be released in situ upon a specific trigger such as temperature (in the current design), pH or oxidative stress.

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