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Nihal Engin Vrana, Agnès Dupret-Bories, Philippe Schultz, Christian Debry, Dominique Vautier and Philippe Lavalle Titanium Microbead-Based Porous Implants: Bead Size Controls Cell Response and Host Integration Advanced Healthcare Materials 3

Version of Record online: 27 JUN 2013 | DOI: 10.1002/adhm.201200369

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Microbead-based porous titanium implants with different granulometries significantly affect cell behavior both in vitro and in vivo. By using smaller microbeads, faster filling of the pores is achieved in vitro and also implants with smaller bead size integrated faster with the host in rat and rabbit models. Utilization of such physical features for controlling implant integration can ensure fast, robust attachment for many applications such as dental, tracheal, and hip implants.

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