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Mina Mekhail, Jamal Daoud, Guillermina Almazan and Maryam Tabrizian Rapid, Guanosine 5'-Diphosphate-Induced, Gelation of Chitosan Sponges as Novel Injectable Scaffolds for Soft Tissue Engineering and Drug Delivery Applications Advanced Healthcare Materials 2

Version of Record online: 4 APR 2013 | DOI: 10.1002/adhm.201200371

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Novel injectable chitosan sponges based on rapid ionic crosslinking using guanosine 5′-diphosphate are introduced. The rapid gelation, high water retention, desirable physicochemical properties, soft tissue-like mechanical properties, and excellent cytocompatibility make these injectable sponges promising candidates for tissue regeneration and drug delivery applications.

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