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Stefan T. Yohe, Jonathan A. Kopechek, Tyrone M. Porter, Yolonda L. Colson and Mark W. Grinstaff Triggered Drug Release from Superhydrophobic Meshes using High-Intensity Focused Ultrasound Advanced Healthcare Materials 2

Version of Record online: 17 APR 2013 | DOI: 10.1002/adhm.201200381

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Application of high-intensity focused ultrasound to drug-loaded superhydrophobic meshes affords triggered drug release by displacing an entrapped air layer. The air layer within the superhydrophobic meshes is characterized using direct visualization and B-mode imaging. Drug-loaded superhydrophobic meshes are cytotoxic in an in vitro assay after ultrasound treatment.

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