Mustapha Jamal, Sachin S. Kadam, Rui Xiao, Faraz Jivan, Tzia-Ming Onn, Rohan Fernandes, Thao D. Nguyen and David H. Gracias Bio-Origami Hydrogel Scaffolds Composed of Photocrosslinked PEG Bilayers Advanced Healthcare Materials 2
Hydrogel bilayers containing photoencapsulated cells self-fold into curved and micropatterned bio-origami geometries. Self-folding is driven by differential swelling of the hydrogel layers and a variety of microstructured bilayers can be photopatterned simultaneously. Bio-origami hydrogels can be used to direct the growth of cells into anatomically relevant 3D geometries for long-term cell culture studies.
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