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Hongshuai Li, Therwa Hamza, John E. Tidwell, Nina Clovis and Bingyun Li Unique Antimicrobial Effects of Platelet-Rich Plasma and Its Efficacy as a Prophylaxis to Prevent Implant-Associated Spinal Infection Advanced Healthcare Materials 2

Version of Record online: 27 FEB 2013 | DOI: 10.1002/adhm.201200465

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Platelet-rich-plasma (PRP) shows unique antimicrobial properties both in vitro and in vivo. An implant-associated spinal infection rabbit model shows that PRP treatment leads to a significant reduction in bacterial burdens together with a significant improvement in wound healing. PRP could be an advanced healthcare material against postoperative implant-associated infections.

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