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Leon M. Bellan, Tatiana Kniazeva, Ernest S. Kim, Alla A. Epshteyn, Donald M. Cropek, Robert Langer and Jeffrey T. Borenstein Hybrid Microfluidic Systems: Fabrication of a Hybrid Microfluidic System Incorporating both Lithographically Patterned Microchannels and a 3D Fiber-Formed Microfluidic Network (Adv. Healthcare Mater. 2/2012) Advanced Healthcare Materials 1

Version of Record online: 16 MAR 2012 | DOI: 10.1002/adhm.201290009

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A device containing a 3D microchannel network (fabricated using sacrificial melt-spun microfibers) sandwiched between lithographically patterned microfluidic channels offers improved delivery of soluble compounds to a large volume compared to a simple stack of two microfluidic channel layers. With this improved delivery ability comes an increased fluidic resistance due to the tortuous network of small-diameter channels, report Leon Bellan and co-workers on 164.

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