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Kai Li, Dan Ding, Chandrasekharan Prashant, Wei Qin, Chang-Tong Yang, Ben Zhong Tang and Bin Liu Gadolinium-Functionalized Aggregation-Induced Emission Dots as Dual-Modality Probes for Cancer Metastasis Study Advanced Healthcare Materials 2

Article first published online: 9 JUL 2013 | DOI: 10.1002/adhm.201300135

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A dual-modality imaging probe is developed through integration of gadolinium(III) into fluorescent dots with aggregation-induced emission (AIE). The obtained fluorescent-magnetic AIE dots allow accurate quantification of biodistribution and engraftment in organ tissues with single cell resolution, which provide vital information of cancer cell behavior at postintravasation stage of metastasis.

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