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Deniece Fon, Aswan Al-Abboodi, Peggy P. Y. Chan, Kun Zhou, Peter Crack, David I. Finkelstein and John S. Forsythe Effects of GDNF-Loaded Injectable Gelatin-Based Hydrogels on Endogenous Neural Progenitor Cell Migration Advanced Healthcare Materials 3

Article first published online: 4 MAR 2014 | DOI: 10.1002/adhm.201300287

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An injectable gelatin-based hydrogel is targeted towards the adult rat subventricular zone in an attempt to attract neural progenitors towards the implant. GDNF encapsulation and porosity within the hydrogel prevent glial scar formation; moreover, neuroblasts are attracted to the hydrogels 7 d after implantation.

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