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Y. Wang and F. Caruso Nanoporous Protein Particles Through Templating Mesoporous Silica Spheres Advanced Materials 18

Version of Record online: 21 FEB 2006 | DOI: 10.1002/adma.200501901

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Sequential assembly of protein and polyelectrolyte in mesoporous silica (MS) spheres leads to the formation of nanoporous protein particles (NPPs); the MS templates are removed after the fabrication process (see figure). The NPPs based on catalase show excellent biological activity, with up to 57 % of the activity retained. This strategy offers a novel and effective method of preparing bioactive NPPs of diverse composition, particle size, and shape.

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