A. K. Sinensky and A. M. Belcher Biomolecular Recognition of Crystal Defects: A Diffuse-Selection Approach Advanced Materials 18
Phage display has been used to find an amino acid sequence that shows binding affinity for surface defects in germanium. A general approach called “diffuse selection” is employed to find consensus peptide sequences (see figure) demonstrating binding specificity for highly defective crystal surfaces versus non-defective crystal surfaces. This approach may be useful for selecting semiconductors with specific doping profiles from diffuse targets with large competing backgrounds.
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