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M. L. Becker, J. A. Fagan, N. D. Gallant, B. J. Bauer, V. Bajpai, E. K. Hobbie, S. H. Lacerda, K. B. Migler and J. P. Jakupciak Length-Dependent Uptake of DNA-Wrapped Single-Walled Carbon Nanotubes Advanced Materials 19

Article first published online: 20 MAR 2007 | DOI: 10.1002/adma.200602667

Thumbnail image of graphical abstract

A length threshold for cell uptake of DNA-wrapped single-walled carbon nanotubes (SWNTs) by human lung fibroblasts (IMR90) is identified. Competitive uptake experiments with well-defined and characterized length fractions show that SWNTs above the length threshold are excluded from the cell, whereas SWNTs labeled with Cy3-derivatized DNA below the threshold are able to access the cell interior, as shown in the fluorescence image and on the cover.

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