E-mail a Wiley Online Library Link

Sonja Bauhuber, Constantin Hozsa, Miriam Breunig and Achim Göpferich Delivery of Nucleic Acids via Disulfide-Based Carrier Systems Advanced Materials 21

Version of Record online: 27 JUL 2009 | DOI: 10.1002/adma.200802453

Thumbnail image of graphical abstract

Materials containing disulfide bonds are very promising for the delivery of nucleic acids into cells, because they exploit the redox gradient between the extra- and intracellular compartment. This review gives an overview of the biological rationale for the synthesis of redox-sensitive, disulfide-based carrier systems. In particular, the basic synthesis approaches for introducing disulfide bonds into carrier molecules are presented.

Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf

Required = Required Field