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Yajun Wang, Yan Yan, Jiwei Cui, Leticia Hosta-Rigau, Joan K. Heath, Edouard C. Nice and Frank Caruso Encapsulation of Water-Insoluble Drugs in Polymer Capsules Prepared Using Mesoporous Silica Templates for Intracellular Drug Delivery Advanced Materials 22

Article first published online: 18 JUN 2010 | DOI: 10.1002/adma.201001497

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Water-insoluble compounds were encapsulated in polymer capsules through mesoporous silica nanoparticle-mediated layer-by-layer assembly. The drug-loaded capsules exhibit excellent colloidal stability and high potency to colorectal cancer cells in vitro with similar cytotoxicity to the free drug dissolved in organic solvent.

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