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Conroy Sun, Guillem Pratx, Colin M. Carpenter, Hongguang Liu, Zhen Cheng, Sanjiv Sam Gambhir and Lei Xing Synthesis and Radioluminescence of PEGylated Eu3+-doped Nanophosphors as Bioimaging Probes Advanced Materials 23

Article first published online: 10 MAY 2011 | DOI: 10.1002/adma.201100919

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Lanthanide-doped nanophosphors stimu­lated by high-energy photons or β+-particles display characteristic 590, 615, and 692 nm emissions of the Eu3+ activator. These radioluminescent nanophosphors, produced by a thermo degradation process and coated with poly(ethylene glycol), serve as imaging probes as demonstrated in vivo with matrigel inclusions detected by both a custom X-ray luminescence and a conventional small animal optical imaging system.

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