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Wang Xiao, Wei-Hai Chen, Xiao-Ding Xu, Cao Li, Jing Zhang, Ren-Xi Zhuo and Xian-Zheng Zhang Design of a Cellular-Uptake-Shielding “Plug and Play” Template for Photo Controllable Drug Release Advanced Materials 23

Version of Record online: 4 JUL 2011 | DOI: 10.1002/adma.201101806

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A novel template was designed for photocontrollable drug release. Multiple functional groups can be loaded and unloaded onto the template via UV irradiation. Importantly, the template can inhibit loaded drug being uptaken by normal cells. However, upon the irradiation of UV light to the target site, such as tumor tissues, the loaded drug can be released from the template quickly and thereafter endocytosed by target cells to achieve the desirable cure effect.

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