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Jerome V. Karpiak, Yogesh Ner and Adah Almutairi Density Gradient Multilayer Polymerization for Creating Complex Tissue Advanced Materials 24

Article first published online: 9 FEB 2012 | DOI: 10.1002/adma.201103501

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An adaptable density gradient multilayer polymerization (DGMP) method facilitates simple fabrication of complex multicompartment scaffolds with structurally continuous interfaces. Solvent density liquid-liquid phase segregation compartmentalizes varied mechanical and chemical cues independently. Bulk photopolymerization produces stratified three-dimensional and two-dimensional matrices. Cells attach to patterned adhesion peptides on biomimetic 2D substrates.

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