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Lei Xing, Haoquan Zheng, Yuanyuan Cao and Shunai Che Coordination Polymer Coated Mesoporous Silica Nanoparticles for pH-Responsive Drug Release Advanced Materials 24

Version of Record online: 24 SEP 2012 | DOI: 10.1002/adma.201201742

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Coordination polymer coated mesoporous silica nanoparticles for drug delivery are successfully synthesized. The system ensures that drugs are stored in the mesopores under a physiological environment. Upon H+ stimulus in the endosomal and lysosomal compartments, the drugs are released into the intracellular organelles of cancer cells, effectively killing the cells.

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