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Wendi Zhang, Chi Wang, Zhongjun Li, Zhenzhen Lu, Yiye Li, Jun-Jie Yin, Yu-Ting Zhou, Xingfa Gao, Ying Fang, Guangjun Nie and Yuliang Zhao Unraveling Stress-Induced Toxicity Properties of Graphene Oxide and the Underlying Mechanism Advanced Materials 24

Article first published online: 24 AUG 2012 | DOI: 10.1002/adma.201202678

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Graphene oxide shows stress-induced toxicity properties in vivo under different pathophysiological conditions. A dual-path chemical mechanism, involving the overproduction of hydroxyl radicals and the formation of oxidizing cytochrome c intermediates, is responsible for the toxicity properties.

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