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Xuan Jiang, Wei Qu, Deng Pan, Yong Ren, John-Michael Williford, Honggang Cui, Erik Luijten and Hai-Quan Mao Plasmid-Templated Shape Control of Condensed DNA–Block Copolymer Nanoparticles Advanced Materials 25

Version of Record online: 11 OCT 2012 | DOI: 10.1002/adma.201202932

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DNA-containing micellar nanoparticles with distinctly different and highly uniform morphologies are prepared via condensation of plasmid DNA with a block copolymer of polyethylene glycol and a polycation in solvents of different polarity. Molecular dynamics simulations explain the underlying mechanism.

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