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S. Lai, M. Demelas, G. Casula, P. Cosseddu, M. Barbaro and A. Bonfiglio Ultralow Voltage, OTFT-Based Sensor for Label-Free DNA Detection Advanced Materials 25

Article first published online: 2 OCT 2012 | DOI: 10.1002/adma.201202996

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An organic ultralow voltage field effect transistor for DNA hybridization detection is presented. The transduction mechanism is based on a field-effect modulation due to the electrical charge of the oligonucleotides, so label-free detection can be performed. The device shows a sub-nanometer detection limit and unprecedented selectivity with respect to single nucleotide polymorphism.

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