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Jae Sung Lee and William L. Murphy Functionalizing Calcium Phosphate Biomaterials with Antibacterial Silver Particles Advanced Materials 25

Article first published online: 26 NOV 2012 | DOI: 10.1002/adma.201203370

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Antimicrobial silver particles are created on calcium phosphate (CaP) biomaterials by sequentially incubating in citric acid and silver nitrate solutions. The subsequent silver release kinetics and released dosage are controlled by simply changing the solution conditions during growth of silver particles. Released silver efficiently suppresses the growth of gram-positive Staphylococcus aureus and gram-negative Escherichia coli without significant cytotoxicity to eukaryotic cells.

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