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Naveen Gandra and Srikanth Singamaneni Bilayered Raman-Intense Gold Nanostructures with Hidden Tags (BRIGHTs) for High-Resolution Bioimaging Advanced Materials 25

Article first published online: 15 NOV 2012 | DOI: 10.1002/adma.201203415

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Conventional SERS probes suffer from limited brightness and poor reproducibility and stability making them unsuitable for routine in vivo applications. A novel class of layered SERS probes is demonstrated in which individual nanostructures host electromagnetic hotspots, thus increasing brightness by more than two orders magnitide compared to conventional individual nanostructures.

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