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Hongliang Liu, Xueli Liu, Jingxin Meng, Pengchao Zhang, Gao Yang, Bin Su, Kang Sun, Li Chen, Dong Han, Shutao Wang and Lei Jiang Hydrophobic Interaction-Mediated Capture and Release of Cancer Cells on Thermoresponsive Nanostructured Surfaces Advanced Materials 25

Article first published online: 19 NOV 2012 | DOI: 10.1002/adma.201203826

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Capture and release of cancer cells: a thermoresponsive nanostructured surface is designed to reversibly capture and release cancer cells, wherein hydrophobic interaction helps the realization of target capture/release of cancer cells. The unique nature of the designed platform is based on the synergistic effect of hydrophobic interactions between the smart surface and the hydrophobic anchor (i.e., biotin-BSA), and topographic interactions between the nanostructured substrates and cancer cells.

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