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Yanlan Liu, Kelong Ai, Jianhua Liu, Mo Deng, Yangyang He and Lehui Lu Dopamine-Melanin Colloidal Nanospheres: An Efficient Near-Infrared Photothermal Therapeutic Agent for In Vivo Cancer Therapy Advanced Materials 25

Version of Record online: 21 DEC 2012 | DOI: 10.1002/adma.201204683

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A new generation of photothermal therapeutic agents based on biopolymer dopamine-melanin colloidal nanospheres is described. Benefitting from their naturally wide distribution in humans, dopamine-melanin colloidal nanospheres exhibit robust biocompatibility and biodegradability, and provide up to 40% photothermal conversion efficiency. After administration, they can efficiently damage tumors at low power density and short irradiation time without damaging healthy tissues.

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