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Geertrui Tavernier, Barbara Mlody, Jo Demeester, James Adjaye and Stefaan C. De Smedt Current Methods for Inducing Pluripotency in Somatic Cells Advanced Materials 25

Version of Record online: 26 MAR 2013 | DOI: 10.1002/adma.201204874

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The emerging field of iPSCs evokes a wave of excitement in regenerative medicine. Although iPSCs create numerous opportunities, researchers are faced with several difficult challenges. One of the main obstacles is to avoid insertional mutagenesis during the reprogramming process. This review describes the progress made in iPSC producing techniques since its initial discovery in 2006.

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