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Gregory N. Grover, Rebecca L. Braden and Karen L. Christman Oxime Cross-Linked Injectable Hydrogels for Catheter Delivery Advanced Materials 25

Version of Record online: 12 MAR 2013 | DOI: 10.1002/adma.201205234

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Catheter delivery of therapeutic materials is important for developing minimally invasive treatment approaches. However, the majority of injectable materials gel rapidly upon mixing and/or heating to body temperature. The application of an oxime cross-linked hydrogel system is demonstrated. The system has a broad range of tunable gelation rates, is capable of injection through a catheter, and exhibits rapid gelation upon injection into tissue.

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