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Yu Chen, Hangrong Chen and Jianlin Shi In Vivo Bio-Safety Evaluations and Diagnostic/Therapeutic Applications of Chemically Designed Mesoporous Silica Nanoparticles Advanced Materials 25

Version of Record online: 17 MAY 2013 | DOI: 10.1002/adma.201205292

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Significant progress in nano-biotechnology has promoted the biomedical evaluation and diagnostic/therapeutic applications of mesoporous silica nanoparticles (MSNs) from extensive in vitro research towards preliminary in vivo evaluation. This comprehensive review highlights the recent progresses in the chemical design and engineering of MSN-based biomaterials for in vivo biomedical applications.

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