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Jinbo Zhu, Libing Zhang, Tao Li, Shaojun Dong and Erkang Wang Enzyme-Free Unlabeled DNA Logic Circuits Based on Toehold-Mediated Strand Displacement and Split G-Quadruplex Enhanced Fluorescence Advanced Materials 25

Version of Record online: 28 FEB 2013 | DOI: 10.1002/adma.201205360

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Adopting fluorescence of PPIX enhanced by a split G-quadruplex and toehold mediated strand displacement reaction, a series of unlabeled fluorescent logic gates is set up and some of them are cascaded into circuits. Controlled release of PPIX, which is also a photosensitizer in photodynamic diagnosis and therapy, is realized by this circuit, making it a wise choice for DNA computing.

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