Luo Gu, Laura E. Ruff, Zhengtao Qin, Maripat Corr, Stephen M. Hedrick and Michael J. Sailor Nanoparticles for Imunotherapy: Multivalent Porous Silicon Nanoparticles Enhance the Immune Activation Potency of Agonistic CD40 Antibody (Adv. Mater. 29/2012) Advanced Materials 24
When multiple copies of an antibody to the immunostimulatory receptor CD40 are attached to a nanoparticle of porous silicon, they are able to activate dendritic B cells more effectively than the same number of unbound, free antibodies. Further details can be found in the article by Michael Sailor and co-workers on page 3981.
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