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Laura Moore, Edward Kai-Hua Chow, Eiji Osawa, J. Michael Bishop and Dean Ho Diamond-Lipid Hybrids Enhance Chemotherapeutic Tolerance and Mediate Tumor Regression Advanced Materials 25

Article first published online: 15 APR 2013 | DOI: 10.1002/adma.201300343

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Self-assembled nanodiamond-lipid hybrid particles (NDLPs) harness the potent interaction between the nanodiamond (ND)-surface and small molecules, while providing a mechanism for cell-targeted imaging and therapy of triple negative breast cancers. Epidermal growth factor receptor-targeted NDLPs are highly biocompatible particles that provide cell-specific imaging, promote tumor retention of ND-complexes, prevent epirubicin toxicities and mediate regression of triple negative breast cancers.

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