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Jiwei Cui, Robert De Rose, James P. Best, Angus P. R. Johnston, Sheilajen Alcantara, Kang Liang, Georgina K. Such, Stephen J. Kent and Frank Caruso Mechanically Tunable, Self-Adjuvanting Nanoengineered Polypeptide Particles Advanced Materials 25

Article first published online: 10 MAY 2013 | DOI: 10.1002/adma.201300981

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DNA-loaded polypeptide particles are prepared via templated assembly of mesoporous silica for the delivery of adjuvants. The elasticity and cargo-loading capacity of the obtained particles can be tuned by the amount of cross-linker used to stabilize the polypeptide particles. The use of polypeptide particles as biocarriers provides a promising method for vaccine delivery.

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