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Juan Jin, Yongzheng Xing, Yanli Xi, Xueli Liu, Tao Zhou, Xinxin Ma, Zhongqiang Yang, Shutao Wang and Dongsheng Liu A Triggered DNA Hydrogel Cover to Envelop and Release Single Cells Advanced Materials 25

Article first published online: 9 JUL 2013 | DOI: 10.1002/adma.201301175

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We develop an enzyme-triggered permeable DNA hydrogel cover to envelop and release single cells in microwells. The porous structure of the DNA hydrogel allows nutrients and waste to pass through, leading to a cell viability as high as 98%. The design provides a general method to culture, monitor, and manipulate single cells, and has potential applications in cell patterning and studying cell communication.

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