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Aniruddh Solanki, Sy-Tsong Dean Chueng, Perry T. Yin, Rajesh Kappera, Manish Chhowalla and Ki-Bum Lee Axonal Alignment and Enhanced Neuronal Differentiation of Neural Stem Cells on Graphene-Nanoparticle Hybrid Structures Advanced Materials 25

Version of Record online: 4 JUL 2013 | DOI: 10.1002/adma.201302219

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Human neural stem cells (hNSCs) cultured on graphene-nanoparticle hybrid structures show a unique behavior wherein the axons from the differentiating hNSCs show enhanced growth and alignment. We show that the axonal alignment is primarily due to the presence of graphene and the underlying nanoparticle monolayer causes enhanced neuronal differentiation of the hNSCs, thus having great implications of these hybrid-nanostructures for neuro-regenerative medicine.

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