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Nicholas E. Kurland, Tuli Dey, Subhas C. Kundu and Vamsi K. Yadavalli Precise Patterning of Silk Microstructures Using Photolithography Advanced Materials 25

Version of Record online: 20 AUG 2013 | DOI: 10.1002/adma.201302823

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Photolithography is used in conjunction with a “silk fibroin photoresist” to form precise protein microstructures directly and rapidly on a variety of substrates. High-resolution features in two and three dimensions with line widths down to one micrometer are formed. Photo-crosslinked protein structures guide cell adhesion, providing precise spatial control of cells without requiring adhesive ligands.

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