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Shupeng She, Qinqin Li, Bowen Shan, Weijun Tong and Changyou Gao Fabrication of Red-Blood-Cell-Like Polyelectrolyte Microcapsules and Their Deformation and Recovery Behavior Through a Microcapillary Advanced Materials 25

Article first published online: 14 AUG 2013 | DOI: 10.1002/adma.201302875

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Multilayer microcapsules with a biconcave discoidal shape mimicking red blood cells (RBCs) are fabricated. The structure of the RBC-like microcapsules is verified by scanning electron and confocal laser scanning microscopies. The capsules show elastic deformation after being forced through a microcapillary with a smaller diameter, exhibiting a high recovery ratio of ≈90%. When the capsules are coated with hemoglobin (Hb),they are able to reversibly bind and release oxygen.

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