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Huanxiang Yuan, Zhang Liu, Libing Liu, Fengting Lv, Yilin Wang and Shu Wang Cationic Conjugated Polymers for Discrimination of Microbial Pathogens Advanced Materials 26

Version of Record online: 16 APR 2014 | DOI: 10.1002/adma.201400636

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A new cationic poly(phenylene vinylene) derivative (PPV-NMe3+) is synthesized, and it exhibits a differential binding ability to microbial cell walls with different components. By varying the ion strengths of the buffer solution, single PPV-NMe3+ molecules can discriminate fungi, Gram-positive bacteria, and Gram-negative bacteria in a rapid and simple manner. Thus, cationic conjugated polymers exhibit high potential as a diagnostic material for the detection and discrimination of pathogens.

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