E-mail a Wiley Online Library Link

Dr. Wolf-Dieter Fessner, Dipl.-Chem. Gudrun Sinerius, Dipl.-Chem. Achim Schneider, Dipl.-Chem. Matthias Dreyer, Prof. Dr. Georg E. Schulz, Dr. Josefa Badia and Prof. Dr. Juan Aguilar Diastereoselective Enzymatic Aldol Additions: L-Rhamnulose and L-Fuculose 1-Phosphate Aldolases from E. coli Angewandte Chemie International Edition in English 30

Version of Record online: 22 DEC 2003 | DOI: 10.1002/anie.199105551

Thumbnail image of graphical abstract

Two bacterial aldolases, RhuA and FucA, which are readily accessible by overex-pression, catalyze the asymmetric addition of dihydroxyacetone phosphate to various aldehydes. The high degree of enantio-and diastereoselectivity for the L-threo (RhuA) and D-erythro (FucA) stereochemistry of the products and the high stability of the enzymes make it possible to prepare rare carbohydrates and their derivatives as well as other polyhydroxylated compounds.

Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf

Required = Required Field