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Woon-Seok Yeo and Milan Mrksich Self-Assembled Monolayers That Transduce Enzymatic Activities to Electrical Signals Angewandte Chemie International Edition 42

Version of Record online: 10 JUL 2003 | DOI: 10.1002/anie.200250862

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A dynamic substrate that transduces a biological activity into an electrical signal has been developed (see scheme). The enzymatic conversion of a redox-inactive substrate presented at a self-assembled monolayer produced a redox-active product that is monitored electrochemically in real time.

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