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Steven V. Ley and Andrew W. Thomas Modern Synthetic Methods for Copper-Mediated C(aryl)[BOND]O, C(aryl)[BOND]N, and C(aryl)[BOND]S Bond Formation Angewandte Chemie International Edition 42

Article first published online: 11 NOV 2003 | DOI: 10.1002/anie.200300594

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The right conditions: The development of new stoichiometric and catalytic variants of the copper-mediated arylation of heteroatoms (see figure) is of particular interest for the synthetic chemist. The authors give a thorough account of the state-of-the-art of the reaction and discuss the broad range of substrates and suitable choices of catalyst systems and reaction conditions.

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