E-mail a Wiley Online Library Link

Hiromi Torii, Masakazu Nakadai, Kazuaki Ishihara, Susumu Saito and Hisashi Yamamoto Asymmetric Direct Aldol Reaction Assisted by Water and a Proline-Derived Tetrazole Catalyst Angewandte Chemie International Edition 43

Version of Record online: 16 MAR 2004 | DOI: 10.1002/anie.200352724

Thumbnail image of graphical abstract

Just add water to improve the performance of direct aldol reactions like that shown. Previously, aldehydes with high water-affinity or -solubility were considered unsuitable for asymmetric synthesis.

Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf

Required = Required Field