E-mail

E-mail a Wiley Online Library Link

Miguel D. Toscano, Kenneth J. Woycechowsky and Donald Hilvert Minimalist Active-Site Redesign: Teaching Old Enzymes New Tricks Angewandte Chemie International Edition 46

Version of Record online: 23 APR 2007 | DOI: 10.1002/anie.200604205

Thumbnail image of graphical abstract

Reduce, reuse, recycle: Enzymes catalyze a wide variety of chemical reactions. However, suitable enzymatic catalysts are lacking for many useful transformations. New catalytic activities arise from mutations in the active site, suggesting that the pool of existing enzymes can be a promising starting point for the creation of catalysts for nonbiological reactions. Often, a single point mutation is sufficient to endow an enzyme with a new function.

Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf

Required = Required Field

SEARCH