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Michiya Matsusaki, Koji Kadowaki, Yoshio Nakahara and Mitsuru Akashi Fabrication of Cellular Multilayers with Nanometer-Sized Extracellular Matrix Films Angewandte Chemie International Edition 46

Version of Record online: 14 MAY 2007 | DOI: 10.1002/anie.200701089

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Layer it on: Cellular multilayers were fabricated by preparing nanometer-sized extracellular matrix (ECM) films (6-nm thick) with fibronectin (FN) and gelatin on the surface of each cell layer. The four-layer cellular architecture was well organized and self-standing. Xenogenic human bilayer architectures similar to blood vessels were prepared by fabrication of the nanofilms on cell surfaces.

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