Chryssostomos Chatgilialoglu, Mila D'Angelantonio, Maurizio Guerra, Panagiotis Kaloudis and Quinto G. Mulazzani A Reevaluation of the Ambident Reactivity of the Guanine Moiety Towards Hydroxyl Radicals Angewandte Chemie International Edition 48
Radically different: Contrary to previous proposals, the main reaction of the HO. radical with guanosine or 2′-deoxyguanosine is the hydrogen abstraction from the NH2 moiety to give a guanyl radical. This radical, characterized by a broad band in the visible region (around 610 nm), undergoes tautomerization to the most stable isomer.
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