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Chun-Hua Lu, Huang-Hao Yang, Chun-Ling Zhu, Xi Chen and Guo-Nan Chen A Graphene Platform for Sensing Biomolecules Angewandte Chemie International Edition 48

Version of Record online: 27 MAY 2009 | DOI: 10.1002/anie.200901479

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Sensitive platform: The use of graphene oxide (GO) as a platform for the sensitive and selective detection of DNA and proteins is presented. The interaction of GO and dye-labeled single-stranded DNA leads to quenching of the dye fluorescence. Conversely, the presence of a target DNA or protein leads to the binding of the dye-labeled DNA and target, releasing the DNA from GO, thereby restoring the dye fluorescence (see picture).

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