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Gwilherm Evano, Alexis Coste and Kévin Jouvin Ynamides: Versatile Tools in Organic Synthesis Angewandte Chemie International Edition 49

Version of Record online: 30 MAR 2010 | DOI: 10.1002/anie.200905817

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A world of possibilities: Ynamides display an exceptionally fine balance between stability and reactivity, and they offer multiple opportunities for the inclusion of nitrogen-based functionalities into organic molecules (see scheme; EWG=electron-withdrawing group). Recent breakthroughs in the preparation of these substrates have revitalized interest in nitrogen-substituted alkynes. Recent developments in this area are highlighted.

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