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Zhenda Lu, Miaomiao Ye, Ni Li, Wenwan Zhong and Yadong Yin Self-Assembled TiO2 Nanocrystal Clusters for Selective Enrichment of Intact Phosphorylated Proteins Angewandte Chemie International Edition 49

Version of Record online: 12 FEB 2010 | DOI: 10.1002/anie.200906648

Thumbnail image of graphical abstract

Mesoporous traps: The title clusters were fabricated through self-assembly of nanocrystals in emulsion droplets and subsequent protective calcination. The specific affinity offered by the metal oxide and the size-exclusion mechanism enabled by the mesoporous structure enable the use of these clusters for efficient enrichment of intact phosphorylated proteins from complex biological samples (see picture).

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