Xiaolin Wang, Jing Huang, Yangyang Zhou, Shengyong Yan, Xiaocheng Weng, Xiaojun Wu, Minggang Deng and Xiang Zhou Conformational Switching of G-Quadruplex DNA by Photoregulation Angewandte Chemie International Edition 49
Bend and stretch… bend and stretch… An azobenzene derivative was used to induce reversible stretching and folding of G-quadruplex DNA upon photoirradiation (see picture). The G quadruplex formed in the presence of the trans isomer was dissociated by irradiation with UV light, and the resulting open oligomer was refolded into a G quadruplex under visible light. This nanodevice thus converts light directly into mechanical work.
Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf