Prof. Jin-Woo Kim, Dr. Jeong-Hwan Kim and Prof. Russell Deaton DNA-Linked Nanoparticle Building Blocks for Programmable Matter Angewandte Chemie International Edition 50
One step at a time: DNA linkers were placed at defined locations and in defined 3D orientations on a colloidal nanoparticle. Because the implemented ligand-replacement strategy was carried out sequentially, DNA linkers maximally segregated, producing a nanoparticle with linkers at 90 or 180° angles (see picture). These building blocks should enable assembly of anisotropic nanostructures with precisely designed geometry and complex functionality.
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