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Dr. Kaihang Wang, Mag. Wolfgang H. Schmied and Dr. Jason W. Chin Reprogramming the Genetic Code: From Triplet to Quadruplet Codes Angewandte Chemie International Edition 51

Version of Record online: 19 JAN 2012 | DOI: 10.1002/anie.201105016

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On all fours: Recent work has used quadruplet codons to encode unnatural amino acids. Multiple unnatural amino acids have been incorporated into proteins through orthogonal protein translation using a quadruplet decoding ribosome (see figure; mutations to ribosome are shown in red).

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