Dr. Kaihang Wang, Mag. Wolfgang H. Schmied and Dr. Jason W. Chin Reprogramming the Genetic Code: From Triplet to Quadruplet Codes Angewandte Chemie International Edition 51
On all fours: Recent work has used quadruplet codons to encode unnatural amino acids. Multiple unnatural amino acids have been incorporated into proteins through orthogonal protein translation using a quadruplet decoding ribosome (see figure; mutations to ribosome are shown in red).
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